We explored how the gut microbiota influences atrial fibrillation (AF) caused by the cancer drug ibrutinib. Using advanced techniques like gene sequencing and microbiota transplantation, we identified that ibrutinib decreases the Lactobacillus gasseri levels, which raises AF risk in rats.
Remarkably, when we supplemented with L. gasseri or its byproduct, butyrate, we found it effectively prevented AF linked to ibrutinib. This study suggests targeting gut microbes could be a promising strategy to manage drug-related heart issues.
Read More
9
Qianshan Huoxue Gao improves ACS
Efficacy and Mechanism of Qianshan Huoxue Gao in Acute Coronary Syndrome via Regulation of Intestinal Flora and Metabolites.
We examined how Qianshan Huoxue Gao (QS) affects acute coronary syndrome (ACS) using an experimental model with rats. These rats underwent a surgical procedure to induce heart problems and were treated with QS, alongside a control group for comparison.
After 28 days of treatment, we observed that QS improved heart function and restored a healthier balance of gut bacteria, similar to results seen with atorvastatin, a conventional medication. Our findings suggest that ethanolamine, a metabolite linked to QS, plays a significant role in helping manage ACS.
Read More
8
Gut microbiota transplant benefits heart health
Transplant of gut microbiota ameliorates metabolic and heart disorders in rats fed with a hypercaloric diet by modulating microbial metabolism and diversity.
We explored how transplanting gut microbiota affects heart disease linked to metabolic syndrome in rats. By giving rats with metabolic issues probiotics derived from healthy gut bacteria, we observed a positive change in their gut microbiome.
Over nine weeks, the transplant reduced harmful bacteria and restored healthy bacterial levels, improving their weight, blood sugar, triglycerides, and cholesterol.
Ultimately, this study suggests that gut microbiota transplants can be a promising approach to enhancing heart health and treating metabolic disorders.
Read More
Most Useful Reviews
9
Long-term relief
15 people found this helpful
Thrush winner! In one of the "Elements" series from the "Dynasty" project, I read about Lactobacillus rhamnosus, a bacterium that aids women with gynecological issues. After my oncology treatment and surgery disrupted my microflora, I felt discomfort and had thrush. I found "Fem Dophilus" on IHerb, which contains Lactobacillus rhamnosus and Lactobacillus reuteri. After two courses with a month's break, I noticed improvements within two weeks. Years have passed, and the problems have not returned. I've recommended it to friends and family, and as far as I know, it has helped them all.
Read More
9
Essential for pregnancies
1 people found this helpful
Ladies, this is a quality product you can't do without. It tackles issues down there effectively and has been indispensable for my health during three pregnancies when Candida and infections were likely. This is the only women's probiotic I’ve seen real results with.
Read More
9
Effective treatment
It was effective in improving women's health issues.
We explored how the gut microbiota influences atrial fibrillation (AF) caused by the cancer drug ibrutinib. Using advanced techniques like gene sequencing and microbiota transplantation, we identified that ibrutinib decreases the Lactobacillus gasseri levels, which raises AF risk in rats.
Remarkably, when we supplemented with L. gasseri or its byproduct, butyrate, we found it effectively prevented AF linked to ibrutinib. This study suggests targeting gut microbes could be a promising strategy to manage drug-related heart issues.
Read More
9
Shenxiang Suhe pill improves cardiac health
Shenxiang Suhe pill improves cardiac function through modulating gut microbiota and serum metabolites in rats after acute myocardial infarction.
We explored the impact of Shenxiang Suhe pill (SXSH) on heart health by examining its effects on gut bacteria and blood metabolites in rats with acute myocardial infarction.
Using a controlled study setup, we found that administering a specific dose of SXSH improved heart function significantly, as indicated by increased ejection fraction and reduced heart damage markers.
However, the benefits were diminished when antibiotics were introduced, highlighting the importance of gut microbiota in this process.
Read More
9
Qianshan Huoxue Gao improves ACS
Efficacy and Mechanism of Qianshan Huoxue Gao in Acute Coronary Syndrome via Regulation of Intestinal Flora and Metabolites.
We examined how Qianshan Huoxue Gao (QS) affects acute coronary syndrome (ACS) using an experimental model with rats. These rats underwent a surgical procedure to induce heart problems and were treated with QS, alongside a control group for comparison.
After 28 days of treatment, we observed that QS improved heart function and restored a healthier balance of gut bacteria, similar to results seen with atorvastatin, a conventional medication. Our findings suggest that ethanolamine, a metabolite linked to QS, plays a significant role in helping manage ACS.
Read More
8
Gut microbiota transplant benefits heart health
Transplant of gut microbiota ameliorates metabolic and heart disorders in rats fed with a hypercaloric diet by modulating microbial metabolism and diversity.
We explored how transplanting gut microbiota affects heart disease linked to metabolic syndrome in rats. By giving rats with metabolic issues probiotics derived from healthy gut bacteria, we observed a positive change in their gut microbiome.
Over nine weeks, the transplant reduced harmful bacteria and restored healthy bacterial levels, improving their weight, blood sugar, triglycerides, and cholesterol.
Ultimately, this study suggests that gut microbiota transplants can be a promising approach to enhancing heart health and treating metabolic disorders.
Read More
8
Probiotics may reduce heart injury
Preventive impact of probiotic supplements on heart injury and inflammatory indices in a rat model of myocardial infarction: histopathological and gene expression evaluation.
We evaluated the role of probiotic supplements in protecting the heart, specifically using Lactobacillus reuteri along with other strains in rats prior to induced heart injury.
Our findings showed that probiotics reduced the severity of cardiac damage, decreased inflammation, and lowered gene expression linked to heart issues.
While the results are promising and suggest that probiotics could play a protective role against cardiac injuries, further research is essential to fully understand their effectiveness in managing heart disease.
Thrush winner! In one of the "Elements" series from the "Dynasty" project, I read about Lactobacillus rhamnosus, a bacterium that aids women with gynecological issues. After my oncology treatment and surgery disrupted my microflora, I felt discomfort and had thrush. I found "Fem Dophilus" on IHerb, which contains Lactobacillus rhamnosus and Lactobacillus reuteri. After two courses with a month's break, I noticed improvements within two weeks. Years have passed, and the problems have not returned. I've recommended it to friends and family, and as far as I know, it has helped them all.
Read More
9
Essential for pregnancies
1 people found this helpful
Ladies, this is a quality product you can't do without. It tackles issues down there effectively and has been indispensable for my health during three pregnancies when Candida and infections were likely. This is the only women's probiotic I’ve seen real results with.
Read More
9
Effective treatment
It was effective in improving women's health issues.
Read More
9
Effective against Candida
4 people found this helpful
Very good! I’ve repurchased many times! It has an absolute effect on Candida. I experience fewer problems with my body, and Candida no longer affects me. I take three capsules of Jarrow Formulas Fem Dophilus nightly, in addition to a California Gold Nutrition LactoBif Probiotic. I feel no discomfort, and I’m consistently satisfied with this product! If you find my comment useful, please like it, thanks!
Read More
8
Colossal benefits
3 people found this helpful
Great supplement for women's health! I trust the quality of this brand as they use quality ingredients. Not only has my intestinal function improved, but my gynecological issues have also decreased. The benefits are tremendous, and I highly recommend it!
Heart disease refers to a range of conditions that affect the heart's function and overall health. This umbrella term includes various cardiovascular issues such as coronary artery disease, which is caused by the buildup of plaque in the arteries; heart rhythm problems (arrhythmias); and heart defects present at birth (congenital heart defects). Additionally, heart disease encompasses conditions related to the heart muscle, such as cardiomyopathy, and the heart's valves, which might not open or close properly. The effects of heart disease can be significant, impacting not only physical health but also quality of life, making prevention and timely medical intervention crucial.
Several risk factors contribute to the development of heart disease, including high blood pressure, high cholesterol levels, diabetes, obesity, poor diet, physical inactivity, and smoking. Genetics also play a role, as heart disease can run in families. To mitigate the risks, healthcare professionals typically recommend lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and avoiding tobacco use. For those already diagnosed with heart disease, treatment options can vary widely, ranging from lifestyle modifications to medications and, in severe cases, surgical interventions. Understanding the nature of heart disease and its risk factors is an essential step toward prevention and effective management.
Lactobacillus is a genus of bacteria that plays a crucial role in the fermentation of various foods and is found naturally in the human gut. Known for their probiotic properties, strains of Lactobacillus are commonly utilized in the production of yogurt, sauerkraut, and other fermented products. They are characterized by their rod-shaped structure and ability to convert sugars into lactic acid, which not only helps preserve food but also contributes to the tangy flavor of fermented foods.
In addition to their culinary uses, Lactobacillus bacteria can offer several health benefits. They are known to support gut health by enhancing the balance of beneficial bacteria in the microbiome, potentially aiding in digestion and alleviating symptoms of issues like irritable bowel syndrome (IBS). Regular consumption of Lactobacillus-containing foods or supplements may also bolster the immune system and improve overall digestive health. With a growing interest in gut health, Lactobacillus remains a key player in both dietary and therapeutic contexts.
Recent research suggests that probiotics, including Lactobacillus, may play a role in heart health. Probiotics can influence cholesterol levels, blood pressure, and inflammation — all factors associated with heart disease. Certain strains of Lactobacillus have shown promise in reducing LDL cholesterol and triglyceride levels, which are critical for maintaining cardiovascular health. Additionally, Lactobacillus may improve gut health, offering a beneficial relationship between gut microbiota and overall heart function.
While the evidence is still evolving, incorporating Lactobacillus through fermented foods like yogurt, kefir, or supplements could provide additional health benefits. However, it's essential to approach this as part of a broader lifestyle strategy, including a balanced diet, regular exercise, and medical guidance from healthcare professionals. As always, individuals with specific health conditions should consult their doctor before starting any new supplement regimen to ensure safety and efficacy.
Based on user reviews, the timeframe for seeing results from this supplement can vary, but many users report experiencing positive effects relatively quickly. Several reviews indicate improvements within just a few days to a couple of weeks of starting the supplement. For instance, one user noted feeling relief by the next morning after taking their first capsules during an exacerbation, with symptoms disappearing by the second day (Read Review). Additionally, another user suggests that consistent use over time can lead to significant improvements, with one reviewer describing their experience after a complete six-month regimen as particularly effective for managing their condition (Read Review).
While individual responses may vary, many users emphasize the importance of consistency in taking the supplement to achieve better health outcomes. One user specifically addressed heart disease concerns and mentioned a significant difference in their health when taking the supplement regularly, indicating that consistent use may enhance its benefits over time (Read Review). It seems that while some can see improvements quickly, a cumulative effect may be experienced with longer-term use.
This supplement is showing promising support from scientific research regarding heart disease, particularly in the context of gut health and its connection to cardiac issues. Notably, a study found that administering probiotics, including Lactobacillus, reduced the severity of cardiac damage in rats subjected to induced heart injuries. This aligns with findings that suggest probiotics may possess protective qualities against heart-related injuries, though further exploration is necessary to fully validate these effects [3]. Additionally, research has uncovered that gut microbiota transplants can positively influence heart health, particularly among conditions associated with metabolic syndrome, suggesting a beneficial interplay between gut bacteria and cardiovascular wellness [2].
Moreover, the incorporation of specific Lactobacillus strains is linked to improvements in cardiac function and reduction of inflammation, which are pivotal in managing and preventing heart disease. For example, interventions enhancing levels of Lactobacillus gasseri demonstrated effectiveness in preventing atrial fibrillation, a serious heart rhythm condition [1]. With multiple studies supporting the potential of gut microbiota modulation to improve heart health, these findings indicate a pathway worth considering for those looking to manage heart disease through dietary supplements that target gut flora.
Users report a range of improvements in symptoms related to women's health issues after using this probiotic supplement. Many have found significant relief from conditions such as thrush, vaginitis, and urinary tract infections. For instance, one user shared that after completing two courses over a month, they noticed improvements within just two weeks, with symptoms not returning for years (Read Review). Another reviewer experienced a marked decrease in gynecological issues after taking the supplement consistently, stating that it was particularly effective following infections (Read Review).
Additionally, users have noted improvements in digestive health and overall wellbeing, emphasizing the importance of consistent use. One individual reported that after three years of regular intake, they had not experienced any infections despite stress, indicating a significant positive change in their health condition (Read Review). Another user highlighted a noticeable difference in health when taking the supplement regularly compared to not (Read Review). While these testimonials suggest positive results, individual responses can vary widely.
Users report a variety of experiences when it comes to combining this supplement with other products in managing heart disease. Many emphasize the importance of consistency in taking the probiotic alongside their other supplements. For instance, one reviewer who has struggled with women's health issues, including heart disease, stated they observed positive results when taking this supplement regularly compared to when they did not (Read Review). Additionally, another user mentioned that they take this probiotic along with cranberry supplements and experienced remarkable improvements in their symptoms (Read Review).
Others have noted that the combination of probiotics appears to support overall health better, particularly in relation to maintaining a balance in the microflora, which is often disrupted by health issues that could potentially affect heart health. One user shared that they pair it with another probiotic product and feel consistently satisfied with their results, indicating that the interplay of these supplements may enhance their effectiveness in managing their conditions, including heart disease (Read Review). While individual experiences can vary widely, the trend among users suggests that combining this supplement with others can lead to improved outcomes when tackling the complexities of heart disease.
Based on user reviews, there is no specific recommended dosage for Lactobacillus in treating heart disease mentioned. However, users report various experiences with their intake that suggest consistent use may provide benefits. For instance, one reviewer noted the importance of taking the probiotic regularly, especially for women prone to health issues like heart disease, to notice a significant difference (Read Review). Another review highlighted the overall health improvements and management of related conditions after consistent usage over several years, indicating that long-term commitment to the probiotic may yield positive results (Read Review).
While specific dosing recommendations remain unclear, one reviewer mentioned they take three capsules of a particular brand at night, implying that higher doses may be beneficial for acute situations, but then they reduced it to a single capsule once they noted improvements (Read Review). Overall, while users agree on the efficacy of Lactobacillus in managing women's health issues, including potential heart disease implications, they appear to advocate for personalized dosing based on individual experiences and health conditions.
9
Quick relief
2 people found this helpful
It helps me personally! Almost immediately after taking my first capsules during an exacerbation, I felt relief by the next morning. Symptoms disappeared by the second day, allowing me to reduce my dosage to one capsule. I plan to order more packaging!
7.5
Noticeable improvement
1 people found this helpful
I discovered this product two years ago while managing a female-related disease. After consistent use, I’ve seen significant improvements against vaginitis. It appears to be notably effective after a complete six-month regimen. The capsules are easy to take and do not require refrigeration.
7.5
Noticeable difference
I have noticed a significant difference between the days I took it regularly and the days I did not, so I would recommend it to those prone to women's health issues, including heart disease, to take it consistently.
9
Long-term relief
15 people found this helpful
Thrush winner! In one of the "Elements" series from the "Dynasty" project, I read about Lactobacillus rhamnosus, a bacterium that aids women with gynecological issues. After my oncology treatment and surgery disrupted my microflora, I felt discomfort and had thrush. I found "Fem Dophilus" on IHerb, which contains Lactobacillus rhamnosus and Lactobacillus reuteri. After two courses with a month's break, I noticed improvements within two weeks. Years have passed, and the problems have not returned. I've recommended it to friends and family, and as far as I know, it has helped them all.
9
Restores microflora
1 people found this helpful
The best female probiotic to restore microflora! It's especially effective after treating infections, thrush, or urinary tract diseases. In a clinical trial, a significant percentage of women experienced improvement in vaginal flora after taking it.
6
Consistent health
2 people found this helpful
I have been taking this consistently for about three years. Even under stress, I used to suffer from vaginitis and cystitis, but this year I haven’t experienced any vaginal infections. It has greatly improved my condition. I also can manage my health better now as the onset of any disease is delayed.
8
Life-changer
Essential items for women's health! This nutritional supplement has become a lifelong product for me after a friend recommended it due to her own struggles with female diseases like cystitis. My symptoms improved remarkably after taking Jarrow Pamdophilus and cranberry supplements. The small pill size makes it easy to swallow, and I believe it has positively affected my digestive health as well.
9
Effective against Candida
4 people found this helpful
Very good! I’ve repurchased many times! It has an absolute effect on Candida. I experience fewer problems with my body, and Candida no longer affects me. I take three capsules of Jarrow Formulas Fem Dophilus nightly, in addition to a California Gold Nutrition LactoBif Probiotic. I feel no discomfort, and I’m consistently satisfied with this product! If you find my comment useful, please like it, thanks!
8
Probiotics may reduce heart injury
Preventive impact of probiotic supplements on heart injury and inflammatory indices in a rat model of myocardial infarction: histopathological and gene expression evaluation.
We evaluated the role of probiotic supplements in protecting the heart, specifically using Lactobacillus reuteri along with other strains in rats prior to induced heart injury.
Our findings showed that probiotics reduced the severity of cardiac damage, decreased inflammation, and lowered gene expression linked to heart issues.
While the results are promising and suggest that probiotics could play a protective role against cardiac injuries, further research is essential to fully understand their effectiveness in managing heart disease.
8
Gut microbiota transplant benefits heart health
Transplant of gut microbiota ameliorates metabolic and heart disorders in rats fed with a hypercaloric diet by modulating microbial metabolism and diversity.
We explored how transplanting gut microbiota affects heart disease linked to metabolic syndrome in rats. By giving rats with metabolic issues probiotics derived from healthy gut bacteria, we observed a positive change in their gut microbiome.
Over nine weeks, the transplant reduced harmful bacteria and restored healthy bacterial levels, improving their weight, blood sugar, triglycerides, and cholesterol.
Ultimately, this study suggests that gut microbiota transplants can be a promising approach to enhancing heart health and treating metabolic disorders.
9
Lactobacillus gasseri prevents AF
Lactobacillus gasseri prevents ibrutinib-associated atrial fibrillation through butyrate.
We explored how the gut microbiota influences atrial fibrillation (AF) caused by the cancer drug ibrutinib. Using advanced techniques like gene sequencing and microbiota transplantation, we identified that ibrutinib decreases the Lactobacillus gasseri levels, which raises AF risk in rats.
Remarkably, when we supplemented with L. gasseri or its byproduct, butyrate, we found it effectively prevented AF linked to ibrutinib. This study suggests targeting gut microbes could be a promising strategy to manage drug-related heart issues.
References
Shi L, Duan Y, Fang N, Zhang N, Yan S, et al. Lactobacillus gasseri prevents ibrutinib-associated atrial fibrillation through butyrate. Europace. 2025;27. doi:10.1093/europace/euaf018
Peña-Ocaña BA, Silva-Flores M, Shotaro T, García-Gálvez L, Hernández-Esquivel L, et al. Transplant of gut microbiota ameliorates metabolic and heart disorders in rats fed with a hypercaloric diet by modulating microbial metabolism and diversity. Biomed Pharmacother. 2024;181:117667. doi:10.1016/j.biopha.2024.117667
Bonab SF, Tahmasebi S, Ghafouri-Fard S, Eslami S. Preventive impact of probiotic supplements on heart injury and inflammatory indices in a rat model of myocardial infarction: histopathological and gene expression evaluation. APMIS. 2025;133:e13479. doi:10.1111/apm.13479
Wu G, Liao J, Zhu X, Zhang Y, Lin Y, et al. Shexiang Baoxin Pill enriches Lactobacillus to regulate purine metabolism in patients with stable coronary artery disease. Phytomedicine. 2024;130:155727. doi:10.1016/j.phymed.2024.155727
Li Y, Liu Y, Cui J, Zhu M, Wang W, et al. Oral-gut microbial transmission promotes diabetic coronary heart disease. Cardiovasc Diabetol. 2024;23:123. doi:10.1186/s12933-024-02217-y
Wang J, Zhang H, Yuan H, Chen S, Yu Y, et al. Prophylactic Supplementation with Lactobacillus Reuteri or Its Metabolite GABA Protects Against Acute Ischemic Cardiac Injury. Adv Sci (Weinh). 2024;11:e2307233. doi:10.1002/advs.202307233
Zhong X, Yan J, Wei X, Xie T, Zhang Z, et al. Shenxiang Suhe pill improves cardiac function through modulating gut microbiota and serum metabolites in rats after acute myocardial infarction. Pharm Biol. 2024;62:1. doi:10.1080/13880209.2023.2289577
Zhao N, Ma Y, Liang X, Zhang Y, Hong D, et al. Efficacy and Mechanism of Qianshan Huoxue Gao in Acute Coronary Syndrome via Regulation of Intestinal Flora and Metabolites. Drug Des Devel Ther. 2023;17:579. doi:10.2147/DDDT.S396649
Huang YL, Xiang Q, Zou JJ, Wu Y, Yu R. Zuogui Jiangtang Shuxin formula Ameliorates diabetic cardiomyopathy mice modulating gut-heart axis. Front Endocrinol (Lausanne). 2023;14:1106812. doi:10.3389/fendo.2023.1106812